Study design, bias and statistics, with appraisal calculators and worked papers.
A full critical appraisal and evidence-based medicine curriculum for emergency clinicians. Twenty-three chapters covering descriptive statistics, choosing a statistical test, study design, bias, confounding, intention-to-treat, confidence intervals, NNT, diagnostic accuracy and likelihood ratios, ROC curves, Bayesian inference, meta-analysis and GRADE. Six working calculators (2x2 diagnostic accuracy, pre-test to post-test probability, treatment effect and NNT, fragility index, sample size, descriptive statistics), five appraisal checklists, six worked appraisals of landmark trials, and a gallery of eight annotated figures of the plots that appear in journal articles.